BIOLOGICAL SCAFFOLDS
Actifit®
Biodegradable, Synthetic Scaffold for Meniscus Repair
BIOLOGICAL SCAFFOLDS
Actifit®
Biodegradable, Synthetic Scaffold for Meniscus Repair
BIOLOGICAL SCAFFOLDS
Actifit®
What is Actifit®?
Actifit® is a biodegradable, porous scaffold made from proprietarypolymer, designed to
help restore meniscal function and tissue loss.
How does Actifit® work?
Partial meniscectomy outcomes can result in chronic knee pain, arthritis, and a dramatic increase in the risk of a future knee replacement.
Actifit® helps facilitate the human body’s natural healing process by providing a scaffold to fill the injured area and allow blood flow and cells to stimulate new tissue growth.
Over time, the bioabsorbable scaffold is replaced with new tissue growth to support the function of the meniscus.
Hear from our doctors
ACTIfit® is a biodegradable, synthetic scaffold made from proprietary polymer, designed to help restore meniscal function and tissue loss.
Irreparable major meniscal tears pose a very difficult problem in the young and active patients. It is extremely important to preserve the meniscus to avoid degenerative knee joint progression. Increased awareness of potentially detrimental outcomes following partial meniscectomy led to the development of a novel meniscal scaffold, Actifit®.
Regenerate Meniscal Tissue, Restore Knee Function
Actifit® has been shown to be a safe, effective implant, for the treatment of patients with pain as a result of segmental medial meniscus loss at 2 years [1, 2]. It supports the in-growth of new “meniscus like” tissue with the aim of alleviating postmeniscectomy knee pain and preventing further articular cartilage degeneration, thus improving the function of the patient’s knee [2] and maintaining the active lifestyle.
Reference
- Peter Verdonk,*y MD, PhD, Philippe Beaufils,z MD, Johan Bellemans,§ MD, PhD, Patrick Djian,|| MD, Eva-Lisa Heinrichs,{ MD, PhD,
Wouter Huysse,# MD, Heinz Laprell, MD, Rainer Siebold,yy MD, PhD, Rene´ Verdonk,y MD, PhD, and the Actifit Study Groupzz.
Successful Treatment of Painful Irreparable Partial Meniscal Defects With a Polyurethane Scaffold -Two-Year Safety and Clinical
Outcomes. American Journal of Sports Medicine, published on February 9, 2012 doi:10.1177/0363546511433032 - Turgay Efe , Alan Getgood, Markus D. Schofer, Susanne Fuchs-Winkelmann, Dieter Mann, Ju¨rgen R. J. Paletta, Thomas J. Heyse. The safety and short-term efficacy of a novel polyurethane meniscal scaffold for the treatment of segmental medial meniscus deficiency. Knee Surg Sports Traumatol Arthrosc (2011) DOI 10.1007/s00167-011-1779-3.
Actifit® is a highly porous scaffold made from a biocompatible, slowly degrading polymer with a highly interconnected pore structure
POROUS HONEYCOMB STRUCTURE
- Scaffold facilitates tissue regeneration from the vascularized portion of the meniscus.
ANATOMIC DESIGN & CUSTOM FIT
- Shaped and sized for medial or lateral meniscus defects.
STRONG, FLEXIBLE MATERIAL
- Reliable handling and suture fixation.
BIODEGRADABLE
- Slow degradation, facilitates tissue remodelling.
Actifit® is available in all restructured and private hospitals.
Speak with your orthopaedic surgeon to see if it’s the right option for you.
FAQs
Actifit® is made primarily from an aliphatic polyurethane polymer.
Actifit® is intended for young and/or active patients suffering from chronic painful symptoms after partial meniscal tissue loss or a failed meniscal repair. Speak with your orthopaedic surgeon to assess if it’s the right option for you.
Yes, when performed by qualified orthopaedic surgeons, Actifit® implantation is safe.
Patients may return home after a day or two and resume light activities within weeks. Individual healing times vary; your orthopaedic surgeon will provide a personalized recovery plan.
ACTIFIT helps facilitate the human body’s natural healing process by providing a scaffold to fill the injured area and allow blood flow and cells to stimulate new tissue growth.
Partial meniscectomy outcomes can result in chronic knee pain, arthritis, and a dramatic increase in the risk of a future knee replacement. The Actifit meniscal scaffold is intended for young and active patients suffering from symptoms after partial meniscal tissue loss. Over time, the bioabsorbable scaffold is replaced with new tissue growth to support the function of the meniscus.
Key Features & Benefits
Porous honeycomb structure that facilitates tissue regeneration from the vascularized portion of the meniscus
Anatomic design & custom fit for medial or lateral meniscus configurations
Strong, flexible material for reliable handling and suture fixation
Biocompatible, slowly degrading polymer that facilitates tissue remodelling
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